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This literature review concentrates on the magnitude of cardiovascular diseases in the global population, the mechanism of L-carnitine in cardiovascular function and its possible effects in different cardiovascular diseases, the side effects and risks of its supplementation, debates, and controversies on its role, and future directions in the context of currently gathered research and applications

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For example, through LC-MS/MS technology, researchers are able to quantify amino acids and acylcarnitines in plasma, which are considered potential biomarkers of metabolic syndrome